Identification of PTPRZ as a drug target for cancer stem cells in glioblastoma

(National Institutes of Natural Sciences) The research group of Professor Masaharu Noda and Researcher Akihiro Fujikawa of the National Institute for Basic Biology (NIBB) showed that the enzymatic activity of PTPRZ is requisite for the maintenance of stem cell properties and tumorigenicity in glioblastoma cells.